Pilot-scale continuous-flow glass reactor(MF-V6)

MF-V6 glass microchannel reactor is a flexible unit for a lab or kilo-scale environment that can also be used as a small production unit (up to a few tons per year).

  • Temperature range: -55°C-200°C
  • Pressure tolerance: ≤18bar
  • Flow rate: 0-100mL/min
  • Flexible volume: 5.3~11.3ml
  • Summary: MF-V6 small-scale glass continuous flow reactors have integrated pre-heat & heat exchange giving optimal thermal control for challenging flow chemistry applications. V6 flow reactor system (flow reactor used in combination with pumps, heat exchangers, temperature control and pressure regulation) that is designed to readily access extreme temperatures (-25 °C to 200 °C), reaction times and pressure conditions (up to 20 bar). V6 enables previously ‘forbidden’ transformations to be executed within a conventional laboratory, and is ideal for up-scaling with no change in mixing efficiency.

Product Overview

The MF-V6 is a modular, compact, and integrated continuous flow glass microchannel reactor designed for process development and small-scale production.

MF-V6 Continuous-Flow Glass ReactorMF-V6 Continuous-Flow Glass Reactor MF-V6 Continuous-Flow Glass Reactor

  • Enhanced Mass & Heat Transfer: Utilizes a multi-layer design with integrated heat exchange to provide precise thermal control and significantly shorten R&D cycles.

  • Process Visualization: Constructed from premium glass to allow in-situ observation of the reaction, streamlining process exploration and optimization.


Key Features & Advantages
  • High-Efficiency Heat & Mass Transfer: Unique channel geometry substantially improves mixing efficiency and minimizes byproduct formation.

  • Zero Scale-Up Effect: Lab-scale recipes can be directly scaled up to kilogram production with exceptional reproducibility and stability.

  • Maximum Safety: A milliliter-level low hold-up volume combined with multi-layered protective designs mitigates operational risks for highly hazardous and exothermic reactions.

  • Flexible Modularity: Offers highly adaptable assembly and disassembly to effortlessly support single-step or multi-step tandem sequential reactions.

  • Cost-Effective R&D: Requires minimal reagent consumption per run, ensuring high cost-efficiency during experimental stages.

Core Technical Specifications
  • Material: Borosilicate glass

  • Temperature Range: -25°C to 195°C

  • Pressure Range: 0 to 20 bar (Standard operating pressure ≤ 18 bar)

  • Flow Rate Range: 0.1 to 100 mL/min (Maximum throughput up to 6 kg/h)

  • Module Scalability: 1 to 6 modules in standard series connection

Models & Flow Channel Classifications
Three tailored internal flow channel structures are available to suit distinct process conditions:
ModelHold-up VolumeStructural FeatureTarget Conditions & Processes
MF-V6-M(HT)6.0 mLUniversal channelGeneral liquid/gas/liquid-solid mixing (Solid particle size ≤ 50 μm).
MF-V6-M(CRT)11.3 mLContinuous rotationSpecially engineered for continuous crystallization and extended residence time.
MF-V6-M(SAT)5.3 mLSpindle-shapedSpecifically designed for high-viscosity fluids and agglomeration-prone materials.

Video demonstration of MF-V6 continuous flow glass microchannel reactor:

Casenitration,strong exothermic reaction,friedel-Crafts reaction,gas-liquid reaction

nitration,strong exothermic reaction,friedel-Crafts reaction,gas-liquid reaction

The use of micro-reaction continuous flow technology can save land and personnel costs. The new technology has a high degree of automation, greater process controllability, safer production, high production efficiency, low operating costs, and guaranteed product quality. The use of new technology can promote the rapid upgrading of domestic technology and enhance the product's position in the international market. The scope and field of continuous flow synthesis continue to expand, not only including traditional reaction types and the pharmaceutical and fine chemical industries, but also extending to the fields of electrochemistry, photochemistry, microwave chemistry, nanomaterials, and functional materials.

The glass continuous flow microchannel reactor MF-V6 is compatible with all reagents except hot concentrated strong alkali, molten alkali metal, hot concentrated H3PO4, HF, and strong corrosive agents. It can operate stably for a long time. The excellent high light transmittance can realize short wavelength range. The photocatalytic reaction.

In addition, due to the light transmittance of glass, glass microreactors are better than microreactors made of other materials in the direction of photocatalysis.

Small-scale high-throughput continuous flow microchannel reactors have been used in some cases, including nitration reaction, strong exothermic reaction, low-temperature Friedel-Crafts reaction, gas-liquid reaction, Michael addition reaction, Friedel-Crafts alkylation reaction, aldol Condensation reaction (sodium ethoxide), sulfonation reaction, nitration reaction, diazotization reaction, azide reaction, solvent-free reaction, etc.

Product categories: glass reactors, high temperature and high pressure reactors, continuous flow reactors, high flux reactors, small test microchannel reactors, micro reactors, gas-liquid reactors, solid-liquid reactors, photochemical (catalytic) reactors .

Applicable reaction types: liquid-liquid reaction, gas-liquid reaction, compatible partial solid-liquid reaction.