MF-V6 Small-scale Glass Flow Microreactors

MF-V6 Kilo-scale Glass Microchannel Reactor Features:Available in integrated multilayer glass construction for mixing, reaction & heat transfer;Micro channel with modular system to connect multiple reactors in series or parallel;Suitable for various liquid-liquid, gas-liquid homogeneous & multi phase reactions;Useful in photochemical & UV induced reactions

  • Temperature range: -25°C-200°C
  • Pressure tolerance: ≤20bar
  • Flow rate: 0-100mL/min
  • Flexible volume: 3~9ml
  • Summary: MF-V6 small-scale glass continuous flow reactors have integrated pre-heat & heat exchange giving optimal thermal control for challenging flow chemistry applications. V6 flow reactor system (flow reactor used in combination with pumps, heat exchangers, temperature control and pressure regulation) that is designed to readily access extreme temperatures (-25 °C to 200 °C), reaction times and pressure conditions (up to 20 bar). V6 enables previously ‘forbidden’ transformations to be executed within a conventional laboratory, and is ideal for up-scaling with no change in mixing efficiency.

Video demonstration of MF-V6 continuous flow glass microchannel reactor:


1.Salient features of MF-V6 glass continuous flow reactora

· Available in integrated multilayer glass construction for mixing, reaction & heat transfer

· Micro channel with modular system to connect multiple reactors in series or parallel

· Suitable for various liquid-liquid, gas-liquid homogeneous & multi phase reactionsThe MF-V6 series continuous flow reactor is a high-throughput glass microreactor processed from high borosilicate float glass. The four-layer structure design includes the heat exchanger in the reactor to reduce the space occupancy rate. The design of the structure ensures the maximization of mixing efficiency, so that the reaction phase forms multiple vortex staggered states in the reaction phase, and ensures that the reaction phase is fully mixed and reacted in the flow channel.

The MF-V6 series glass microchannel reactor is compatible with all reagents except hot concentrated alkali, molten alkali metal, hot concentrated H3PO4, HF, and strong corrosive agents. It can operate stably for a long time. The excellent high light transmittance can achieve short wavelength Photocatalytic reaction. Compared with the traditional tubular catalysis, the microreactor can also increase the catalysis conditions and promote the formation of reactants through the application of the heat exchange layer.

MF-V6 (9ml) is the maximum liquid holding capacity of the monolithic continuous flow microreactor, thereby prolonging the reaction residence time of the microchannel reactor. Under the conditions of the same flow rate, the larger the liquid holding capacity of the micro-channel reactor, the longer the residence time of the reaction phase in the microreactor, and the more ideal the reaction effect can be achieved for some reactions that require reaction time. This product can also be customized for other models with different specifications of liquid holding capacity, 9ml is the maximum processing depth. The annual throughput can reach 70-80T/year, which can also meet the needs of small-scale experiments and production.

The MF-V6 series of continuous flow reactor are processed from high borosilicate float glass into large-throughput microreactors.

2.MF-V6 Glass Continuous Flow Reaction Systems:

MF-V6 Glass Continuous Flow Reaction Systems

3.Specifications of MF-V6 glass continuous flow reactora

MF-V6 Series  Small-scale Glass Flow Reactors

Model

MF-V6-M

MFV6-M(6)

MF-V6-M(9)

MF-V6S-M

Size

152.4x152.4x 11mm

Material

Borosilicate Glass

Channel Size

/

Channel Length

1.8m

Volume

3ml

6ml

9ml

3ml

Surface to volume ratio(u)

/

/

/

/

Design temperature (°C)

-25°C-200°CCustom-30℃-280℃

*The difference between the glass temperature and the outside temperature is controlled within 70

Design pressure (bar)

20bar(Recommended pressure 1.7Mpa)

Flow rate

0-100mL/min

Features/Advantages

Available in integrated multilayer glass construction for mixing, reaction & heat transfer;

Micro channel with modular system to connect multiple reactors in series or parallel;

Suitable for various liquid-liquid, gas-liquid homogeneous & multi phase reactions;

Useful in photochemical & UV induced reactions;

Process Case

1. Michael addition reaction

2. Friedel-Crafts alkylation reaction

3. Aldol condensation reaction (sodium ethoxide)

4. Sulfonation reaction and nitration reaction

5. Diazotization reaction, azide reaction

6. Solvent-free reaction, 30% liquid-liquid reaction (high probability)


4.
Suitable for type reactions up to A+B=C+Q=D or A+B=C or A+B=Q1 C+D=Q2

Suitable for type reactions up to A+B=C+Q=D or A+B=C or A+B=Q1 C+D=Q2

5.Example Of Applications

The following reactions are done with micromixer or  jet mixer( emulsifier) if 2 phase reaction was carried out.

· Synthesis of semiconducting polymers for OLED applications

· Synthesis of azo dye via azo coupling

·Synthesis of hydroxymethylfurfural (HMF) and furandicarbonacid (FDCA) out of renewable resources

· Synthesis and work up of nitrate ester

· Catalyzed oxidation for synthesis of functional aldehyde

· Synthesis and conversion of diazomethane

· Photochlorination, bromination, alkylation etc.

6.Casenitration,strong exothermic reaction,friedel-Crafts reaction,gas-liquid reaction

nitration,strong exothermic reaction,friedel-Crafts reaction,gas-liquid reaction

The use of micro-reaction continuous flow technology can save land and personnel costs. The new technology has a high degree of automation, greater process controllability, safer production, high production efficiency, low operating costs, and guaranteed product quality. The use of new technology can promote the rapid upgrading of domestic technology and enhance the product's position in the international market. The scope and field of continuous flow synthesis continue to expand, not only including traditional reaction types and the pharmaceutical and fine chemical industries, but also extending to the fields of electrochemistry, photochemistry, microwave chemistry, nanomaterials, and functional materials.

The glass continuous flow microchannel reactor MF-V6 is compatible with all reagents except hot concentrated strong alkali, molten alkali metal, hot concentrated H3PO4, HF, and strong corrosive agents. It can operate stably for a long time. The excellent high light transmittance can realize short wavelength range. The photocatalytic reaction.

In addition, due to the light transmittance of glass, glass microreactors are better than microreactors made of other materials in the direction of photocatalysis.

Small-scale high-throughput continuous flow microchannel reactors have been used in some cases, including nitration reaction, strong exothermic reaction, low-temperature Friedel-Crafts reaction, gas-liquid reaction, Michael addition reaction, Friedel-Crafts alkylation reaction, aldol Condensation reaction (sodium ethoxide), sulfonation reaction, nitration reaction, diazotization reaction, azide reaction, solvent-free reaction, etc.

Application field

· Photochlorination

· Production of Vitamin D

· Photoalkylation

· Production of artemisinin (anti-malaria drug)

· Production of Caprolactam

7.MF-V6 continuous flow microreactor Schematic diagram of the continuous production of nanomaterials case process

MF-V6 continuous flow microreactor Schematic diagram of the continuous production of nanomaterials case process

Product categories: glass reactors, high temperature and high pressure reactors, continuous flow reactors, high flux reactors, small test microchannel reactors, micro reactors, gas-liquid reactors, solid-liquid reactors, photochemical (catalytic) reactors .

Applicable reaction types: liquid-liquid reaction, gas-liquid reaction, compatible partial solid-liquid reaction.