Active Pharmaceutical Ingredient (API)

α-Lobeline Hydrochloride (98% Purity) - Kilogram-Scale Supply

2026-07-20 09:27:02
Product Overview

α-Lobeline Hydrochloride (also known as Lobeline HCl) is a well-established alkaloid salt traditionally used as a potent respiratory stimulant. It acts by selectively stimulating the chemoreceptors of the carotid body, reflexively exciting the respiratory center. It is widely utilized in pharmaceutical formulations targeting respiratory failure (caused by neonatal asphyxia, carbon monoxide poisoning, or central nervous system depressants) and in smoking cessation research.

α-Lobeline Hydrochloride

Leveraging our advanced purification and synthesis technologies, we provide high-quality α-Lobeline Hydrochloride with a guaranteed purity of ≥ 98%. We maintain stable kilogram-scale stock to seamlessly support your needs from pilot scale-up (R&D) to commercial formulation manufacturing.
Core Advantages
  • High Purity (≥ 98.0%): Purified through precise multi-stage crystallization. Impurities, related alkaloids, and heavy metals are strictly controlled to ensure optimal stability and safety in formulation development.

  • Stable Kilogram-Scale Supply: Backed by a robust supply chain and standardized production lines. We offer flexible order sizes from hundreds of grams to multi-kilogram (kg) batches with year-round availability.

  • Rigorous Quality Control (QbD): Produced under strict quality management systems. Every batch comes with a complete analytical package, including COA (Certificate of Analysis), HPLC, MS, and H-NMR spectra.

  • Customization Services: We can customize the particle size distribution (micronization) and specialized protective packaging based on your specific formulation requirements.

Technical Specifications
  • Chemical Name: α-Lobeline hydrochloride / Lobeline HCl

  • CAS Registry Number: 134-63-9

  • Molecular Formula: C₂₂H₂₇NO₂·HCl

  • Molecular Weight: 373.92

  • Appearance: White to off-white crystalline powder; odorless with a bitter taste.

  • Melting Point: 178 – 182 °C

  • Assay / Purity: ≥ 98.0% (HPLC)

  • Standard Packaging: 500g/bag, 1kg/aluminum foil bag, 25kg/fiber drum (Custom small-scale packaging available upon request).

Disclaimer
All chemical products sold by our company are intended solely for laboratory research, export, or pharmaceutical manufacturing R&D. They are not intended for direct human or clinical use.