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(-)-Benzotetramisole ((-)-BTM) - CAS: 950194-37-3, 98% Purity, Kilogram-Scale Supply

2026-07-21 13:56:51
Product Overview

(-)-Benzotetramisole (chemically known as (S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole, commonly abbreviated as (-)-BTM, CAS: 950194-37-3) is a highly acclaimed, powerful chiral organocatalyst in the field of asymmetric organic chemistry. Acting as a non-nucleoside nucleophilic Lewis base, it exhibits exceptional catalytic activity and stereoselectivity in the kinetic resolution (KR) of secondary and tertiary alcohols, asymmetric lactonization, [2+2]/[4+2] cycloadditions, and asymmetric functionalizations of chiral carboxylic acid derivatives.

(-)-Benzotetramisole / (S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole / (-)-BTM

Because this molecule contains a sensitive stereocenter, its synthetic route is lengthy and its chiral resolution is notoriously labor-intensive. Consequently, traditional chemical catalog retailers only supply it in milligram or gram quantities at premium rates. Utilizing our mature directional asymmetric synthesis and advanced purification systems, we have successfully scaled up production. We proudly offer 98% high chemical purity and excellent enantiomeric excess (ee%) ready stock on a stable kilogram-scale (kg-scale) to seamlessly support your chiral drug discovery and industrial pilot scale-up.
 Core Advantages

  • Dual High Standards: Chemical Purity ≥ 98% & Excellent ee%: Refined through precise chiral control and multi-stage fine recrystallization. Enantiomeric impurities and structural process byproducts are strictly restricted to deliver exceptionally high stereochemical induction and chemical yields in asymmetric transformations.

  • Stable Kilogram-Scale Supply Capacity: Backed by a standardized pilot-scale manufacturing facility and a continuous raw material supply chain. We eliminate the market bottleneck of minor catalog reagent quantities, supporting flexible, bulk purchases from hundreds of grams to continuous multi-kilogram batches.

  • Outstanding Catalytic Efficiency: Demonstrates high Turnover Numbers (TON) and remarkable selectivity factors (s-factors) in asymmetric acylations and functionalization assays. This significantly lowers the required catalyst loading, optimizing your current or subsequent formulation costs.

  • Rigorous Quality Control (QbD): Produced under rigid quality management structures. Every single dispatch is accompanied by a thorough testing package, including a COA (Certificate of Analysis), HPLC (Chemical Purity Analysis), H-NMR, and Chiral HPLC charts confirming optical purity.

Technical Specifications

  • Chemical Name: (-)-Benzotetramisole / (S)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole / (-)-BTM

  • CAS Registry Number: 950194-37-3

  • Molecular Formula: C₁₁H₁₂N₂S

  • Molecular Weight: 204.30

  • Appearance: White to off-white crystalline powder.

  • Assay / Purity: Chemical Purity ≥ 98.0% (HPLC) / Superior Enantiomeric Excess (ee%).

  • Standard Packaging: 100g/bottle, 500g/bag, 1kg/aluminum foil bag (Customized airtight, light-proof packaging available upon request).

Disclaimer
All chemical products sold by our company are intended solely for laboratory research, export, chiral process engineering, or industrial manufacturing R&D. They are not intended for use as food additives, cosmetic raw materials, or clinical drugs in humans.


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