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6-Hydroxy-4-quinolinecarboxylic acid (CAS: 4312-44-1) - 98% Purity, Kilogram-Scale Supply

2026-07-21 14:05:12
Product Overview

6-Hydroxy-4-quinolinecarboxylic acid (also known as 6-Hydroxycinchoninic acid, CAS: 4312-44-1) is a highly versatile and valuable quinoline derivative and premium organic building block. By strategically embedding a rigid quinoline heterocycle, a highly reactive carboxylic acid group at the 4-position, and a phenolic hydroxyl group at the 6-position into a single molecular structure, it acts as a critical cornerstone molecule. It is widely utilized in chiral drug synthesis, novel small-molecule oncology/antimicrobial inhibitor discovery, specialized fluorescent dyes, coordination functional materials, and advanced optoelectronic chemicals.

6-Hydroxy-4-quinolinecarboxylic acid / 6-Hydroxycinchoninic acid

Because this compound is highly prone to producing positional isomers and oxidative byproducts during synthesis, conventional isolation and purification are exceptionally difficult. This renders high-purity, kilogram-scale suppliers rare on the global market. Utilizing our mature directional heterocyclic synthesis and advanced multi-stage refinement technologies, we have successfully conquered these technical barriers. We proudly offer 98% high-purity 6-Hydroxy-4-quinolinecarboxylic acid with stable, kilogram-scale (kg-scale) ready stock to seamlessly accelerate your pharmaceutical profiling and novel materials development.
Core Advantages

  • High Polymerization Purity (≥ 98.0%): Refined via specialized crystallization and precision chromatography. Positional isomers, free inorganic salts, and residual solvents are strictly restricted to deliver exceptionally high chemical reactivity and excellent conversion yields in downstream condensation, esterification, and coupling assays.

  • Stable Kilogram-Scale Supply: Backed by a standardized pilot-scale and commercial manufacturing infrastructure with a robust raw material supply chain. We eliminate the market bottleneck of premium, grams-only reagent catalogs, supporting flexible, bulk purchases from hundreds of grams to continuous multi-kilogram batches.

  • Comprehensive Quality Control (QbD): Produced under rigid quality management structures. Every single dispatch is accompanied by a thorough testing package, including a COA (Certificate of Analysis), HPLC (Chemical Purity Analysis), H-NMR, moisture content, and heavy metals reports for complete traceability.

  • Airtight Protective Packaging: To counteract the tendency of phenolic and carboxylic functional groups to undergo oxidation and discoloration under specific environments, the entire packaging cycle is executed in a climate-monitored, moisture-proof facility. Vacuum-sealed pharmaceutical-grade inner bags enclosed in aluminum foil shields guarantee zero quality degradation during long-term storage.

Technical Specifications

  • Chemical Name: 6-Hydroxy-4-quinolinecarboxylic acid / 6-Hydroxycinchoninic acid

  • CAS Registry Number: 4312-44-1

  • Molecular Formula: C₁₀H₇NO₃

  • Molecular Weight: 189.17

  • Appearance: Pale yellow to tan or light yellow crystalline powder.

  • Assay / Purity: ≥ 98.0% (HPLC)

  • Storage Conditions: Store at 2-8°C (or in a cool, dry place), tightly sealed, protected from light, and moisture.

  • Standard Packaging: 100g/bottle, 500g/bag, 1kg/aluminum foil bag, 5kg/fluorinated drum (Customized packaging available upon request).

Disclaimer
All chemical products sold by our company are intended solely for laboratory research, export, small-molecule process engineering, or industrial manufacturing R&D. They are not intended for use as food additives, cosmetic raw materials, or clinical drugs in humans.


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